STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpHYR1_012569Ubiquitin-fold modifier 1; Ubiquitin-like modifier. (87 aa)    
Predicted Functional Partners:
BpHYR1_002222
Ubiquitin-like modifier-activating enzyme 5.
    
 
 0.986
BpHYR1_046656
Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.
   
 
 0.951
BpHYR1_038787
Inactive Ufm1-specific protease 1.
  
 
 
 0.944
BpHYR1_008446
Ufm1-specific protease 2.
    
 
 0.928
BpHYR1_029247
Ufm1-specific protease 2.
    
 
 0.928
BpHYR1_014543
Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...]
    
 
 0.793
BpHYR1_051499
NEDD8-activating enzyme E1 catalytic subunit.
    
 
 0.778
BpHYR1_053683
E3 UFM1-ligase 1.
   
 
 0.766
BpHYR1_022527
DDRGK domain-containing 1.
    
 
 0.717
BpHYR1_005613
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 
 0.708
Your Current Organism:
Brachionus plicatilis
NCBI taxonomy Id: 10195
Other names: B. plicatilis
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