STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpHYR1_026605E3 ubiquitin-ligase RFWD3. (582 aa)    
Predicted Functional Partners:
BpHYR1_006932
Replication A 14 kDa subunit.
    
 
 0.978
BpHYR1_022868
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
   
 
 0.970
BpHYR1_009203
Meiosis-specific with OB domain-containing.
   
 
 0.873
BpHYR1_017783
Replication A 32 kDa subunit.
    
 
 0.859
BpHYR1_028967
Heat shock.
    
  0.602
BpHYR1_026422
Heat shock 83.
    
  0.602
BpHYR1_042621
Heat shock 83.
    
  0.602
BpHYR1_030000
Spindle assembly abnormal 6-like protein.
    
 
 0.597
BpHYR1_008860
Putative palmitoyltransferase ZDHHC16 isoform X5.
    
   0.577
BpHYR1_043305
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
   0.577
Your Current Organism:
Brachionus plicatilis
NCBI taxonomy Id: 10195
Other names: B. plicatilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.