STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpHYR1_018337Malate dehydrogenase. (332 aa)    
Predicted Functional Partners:
BpHYR1_005118
Citrate synthase; Belongs to the citrate synthase family.
  
 0.990
BpHYR1_038485
Fumarate mitochondrial.
  
 0.958
BpHYR1_002517
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.954
BpHYR1_041921
Aspartate cytoplasmic.
   
 0.948
BpHYR1_031619
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.946
BpHYR1_011432
Malate dehydrogenase.
   
0.944
BpHYR1_028120
Aspartate aminotransferase.
   
 0.940
BpHYR1_012932
Fumarate hydratase class I.
  
 
 0.935
BpHYR1_050387
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
  
 0.932
BpHYR1_000646
Phosphoenolpyruvate phosphomutase.
  
 0.925
Your Current Organism:
Brachionus plicatilis
NCBI taxonomy Id: 10195
Other names: B. plicatilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.