Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKV01066.1Transcriptional regulator; IMG reference gene:2509843190; PFAM: AsnC family. (148 aa)    
Predicted Functional Partners:
EKU96370.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
    
 0.869
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
    
 0.704
EKU99526.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.632
EKU97326.1
uroporphyrin-III C-methyltransferase; IMG reference gene:2509846490; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.632
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.612
EKV00862.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.601
EKV02095.1
IMG reference gene:2509844280; PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; Belongs to the aldehyde dehydrogenase family.
  
 
 0.601
EKV00033.1
acyl-CoA synthetase (NDP forming); IMG reference gene:2509842106; PFAM: CoA binding domain; Acetyltransferase (GNAT) family; TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain.
    
  0.598
EKV01067.1
Putative threonine efflux protein; IMG reference gene:2509843191; PFAM: LysE type translocator.
       0.597
EKV01696.1
Malic enzyme; IMG reference gene:2509843857; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; ACT domain.
    
 0.595
Your Current Organism:
Leptolyngbya sp. PCC7375
NCBI taxonomy Id: 102129
Other names: Acrophormium splendidus PCC 7375, Adonisia splendidus PCC 7375, L. sp. PCC 7375, Leptolyngbya sp. PCC 7375
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