STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKV02408.1Hypothetical protein; IMG reference gene:2509844623. (227 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
  
 
 0.989
mfd
Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
 
 
 0.941
EKV00797.1
Hypothetical protein; IMG reference gene:2509842914.
 
 
 0.833
EKV02281.1
DNA/RNA helicase, superfamily I; IMG reference gene:2509844487; PFAM: UvrD/REP helicase.
 
 
 0.826
EKV00864.1
DnaJ-class molecular chaperone with C-terminal Zn finger domain; IMG reference gene:2509842984; PFAM: DnaJ domain.
  
 
 0.811
EKU99312.1
Molecular chaperone GrpE (heat shock protein); IMG reference gene:2509841322; PFAM: Helix-turn-helix.
 
   
 0.799
EKV02406.1
Organic solvent tolerance protein OstA; IMG reference gene:2509844621; PFAM: Protein of unknown function (DUF3769).
 
   
 0.799
EKV02385.1
Putative RNA-binding protein (contains KH domain); IMG reference gene:2509844599; PFAM: KH domain.
  
     0.774
EKV03279.1
Hypothetical protein; IMG reference gene:2509845551.
  
     0.773
EKV03421.1
Hypothetical protein; IMG reference gene:2509845702.
  
     0.773
Your Current Organism:
Leptolyngbya sp. PCC7375
NCBI taxonomy Id: 102129
Other names: Acrophormium splendidus PCC 7375, Adonisia splendidus PCC 7375, L. sp. PCC 7375, Leptolyngbya sp. PCC 7375
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