STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B3RNP5_TRIADInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (189 aa)    
Predicted Functional Partners:
B3RVF1_TRIAD
Pribosyltran domain-containing protein.
  
 0.984
PURA_TRIAD
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family.
   
 0.981
B3RU43_TRIAD
dUTPase domain-containing protein.
  
 0.964
B3RIX3_TRIAD
DM10 domain-containing protein; Belongs to the NDK family.
  
 
 0.961
B3S2N2_TRIAD
Nucleoside diphosphate kinase.
  
 
 0.960
B3S5J6_TRIAD
Nucleoside diphosphate kinase.
  
 0.956
B3RLB4_TRIAD
Thymidylat_synt domain-containing protein.
  
 
 0.955
B3S031_TRIAD
Uncharacterized protein.
  
 
 0.954
B3S727_TRIAD
Uncharacterized protein.
    
 0.954
B3S9D6_TRIAD
MGS domain-containing protein.
     
 0.952
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.