STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pecSTranscriptional regulator PecS; COG: COG1846. (176 aa)    
Predicted Functional Partners:
pecM
Drug/metabolite transporter family membrane protein.
 
   
 0.875
hpcR
Homoprotocatechuate degradative operon repressor; COG: COG1846.
  
     0.581
EGZ49354.1
Hypothetical protein.
       0.572
EGZ49352.1
Nitroreductase; COG: COG0778.
  
 
  0.515
EGZ44414.1
DeoR family transcriptional regulator; COG: COG2378.
  
     0.510
EGZ51129.1
ABC superfamily ATP binding cassette transporter, membrane protein; COG: COG1732.
  
  
 0.469
topA
DNA topoisomerase TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA s [...]
     
 0.431
eamA
EamA family efflux transporter; COG: COG0697.
  
     0.409
Your Current Organism:
Neisseria wadsworthii
NCBI taxonomy Id: 1030841
Other names: N. wadsworthii 9715, Neisseria sp. WC 05-9715, Neisseria wadsworthii 9715, Neisseria wadsworthii WC 05-9715, Neisseria wadsworthii str. 9715, Neisseria wadsworthii strain 9715
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.