STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein RadC; COG: COG2003; Belongs to the UPF0758 family. (229 aa)    
Predicted Functional Partners:
EGY52511.1
ComF/gntX family protein; COG: COG1040.
 
    0.678
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.
 
  
 0.672
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.662
speE2
Spermidine synthase; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.620
topA2
DNA topoisomerase TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA s [...]
     
 0.602
EGY53247.1
Hypothetical protein.
  
    0.536
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.509
dprA
DNA protecting protein DprA; COG: COG0758.
  
  
 0.463
comA
Competence factor transporting permease/ATP-binding protein ComA; COG: COG2333.
 
  
 0.452
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.425
Your Current Organism:
Neisseria shayeganii
NCBI taxonomy Id: 1032488
Other names: N. shayeganii 871, Neisseria shayeganii 871, Neisseria shayeganii str. 871, Neisseria shayeganii strain 871, Neisseria sp. WC 08-871
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.