STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spkDSerine-threonine-protein kinase D. (52 aa)    
Predicted Functional Partners:
mltB
Membrane bound lytic murein transglycosylase B protein.
    
 0.819
ERJ19945.1
tRNA nucleotidyltransferase CCA-adding enzyme protein.
    
 0.819
ERJ19529.1
Membrane-bound lytic peptidoglycan transglycosylase D protein.
    
 0.819
ERJ20512.1
Sporulation related domain protein.
  
 0.816
guaB
Inosine-5'-monophosphate dehydrogenase protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.811
guaA
GMP synthase glutamine-hydrolyzing protein; Catalyzes the synthesis of GMP from XMP.
    
 0.779
ERJ20692.1
Hypothetical protein.
       0.773
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
   
 0.772
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
   
 0.772
ERJ18992.1
N-acetylmuramoyl-L-alanine amidase protein.
    
 0.761
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
Server load: low (26%) [HD]