STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirAFerredoxin--nitrite reductase protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (645 aa)    
Predicted Functional Partners:
cysG
Siroheme synthase protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
  
 0.987
cysJ
Sulfite reductase NADPH flavoprotein alpha-component.
 
 0.984
ycbX
Putative 2Fe-2S cluster-containing protein.
  
 0.976
cysH
Phosphoadenosine phosphosulfate reductase protein.
 
 
 0.967
nirB
Assimilatory nitrite reductase large subunit protein.
   
 0.964
ERJ17834.1
Sulfite reductase NADPH flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
 
 0.963
ERJ19207.1
Sulfite reductase flavoprotein alpha-component.
 
 0.961
cysC
Adenylyl-sulfate kinase protein; Catalyzes the synthesis of activated sulfate.
 
 
 0.926
nasA
Nitrate reductase large subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
    
 0.901
ERJ19982.1
Formate dehydrogenase alpha subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 0.890
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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