STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase protein. (670 aa)    
Predicted Functional Partners:
ERJ20255.1
hydroxymethylglutaryl-CoA reductase protein; Belongs to the HMG-CoA reductase family.
 
 0.998
mvaS
Hydroxymethylglutaryl-CoA synthase protein.
 
 
 0.975
idi
Isopentenyl-diphosphate Delta-isomerase protein; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 0.967
ispA
Geranyltranstransferase protein; Belongs to the FPP/GGPP synthase family.
  
 0.753
ispB
Octaprenyl-diphosphate synthase protein; Belongs to the FPP/GGPP synthase family.
  
 0.753
uppS
Undecaprenyl diphosphate synthase protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
   
 0.697
metF
Methylenetetrahydrofolate reductase protein; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.644
ERJ20082.1
L-lactate dehydrogenase protein.
    
 0.545
ERJ18774.1
Lactate 2-monooxygenase protein.
    
 0.545
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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