node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERJ18159.1 | ERJ18394.1 | SSPSH_002936 | SSPSH_002675 | Serine-threonine-protein kinase PpkA. | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | 0.868 |
ERJ18159.1 | ERJ19258.1 | SSPSH_002936 | SSPSH_001867 | Serine-threonine-protein kinase PpkA. | Two-component sensor histidine kinase protein. | 0.670 |
ERJ18159.1 | cbpA | SSPSH_002936 | SSPSH_002682 | Serine-threonine-protein kinase PpkA. | Curved DNA-binding protein. | 0.676 |
ERJ18159.1 | clpB | SSPSH_002936 | SSPSH_001571 | Serine-threonine-protein kinase PpkA. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.843 |
ERJ18159.1 | clpP | SSPSH_002936 | SSPSH_001623 | Serine-threonine-protein kinase PpkA. | ATP-dependent Clp protease proteolytic subunit protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.425 |
ERJ18159.1 | dnaJ | SSPSH_002936 | SSPSH_002335 | Serine-threonine-protein kinase PpkA. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.621 |
ERJ18159.1 | dnaK | SSPSH_002936 | SSPSH_002334 | Serine-threonine-protein kinase PpkA. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.631 |
ERJ18394.1 | ERJ18159.1 | SSPSH_002675 | SSPSH_002936 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Serine-threonine-protein kinase PpkA. | 0.868 |
ERJ18394.1 | ERJ19258.1 | SSPSH_002675 | SSPSH_001867 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Two-component sensor histidine kinase protein. | 0.989 |
ERJ18394.1 | cbpA | SSPSH_002675 | SSPSH_002682 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Curved DNA-binding protein. | 0.485 |
ERJ18394.1 | clpB | SSPSH_002675 | SSPSH_001571 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.702 |
ERJ18394.1 | clpP | SSPSH_002675 | SSPSH_001623 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | ATP-dependent Clp protease proteolytic subunit protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.478 |
ERJ18394.1 | dnaJ | SSPSH_002675 | SSPSH_002335 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.564 |
ERJ18394.1 | dnaK | SSPSH_002675 | SSPSH_002334 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.728 |
ERJ18394.1 | grpE | SSPSH_002675 | SSPSH_002333 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.579 |
ERJ18394.1 | hspA | SSPSH_002675 | SSPSH_001779 | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | Low molecular weight heat shock protein; Belongs to the small heat shock protein (HSP20) family. | 0.446 |
ERJ19258.1 | ERJ18159.1 | SSPSH_001867 | SSPSH_002936 | Two-component sensor histidine kinase protein. | Serine-threonine-protein kinase PpkA. | 0.670 |
ERJ19258.1 | ERJ18394.1 | SSPSH_001867 | SSPSH_002675 | Two-component sensor histidine kinase protein. | Two-component system NarL family capsular synthesis sensor histidine kinase RcsC protein. | 0.989 |
ERJ19258.1 | cbpA | SSPSH_001867 | SSPSH_002682 | Two-component sensor histidine kinase protein. | Curved DNA-binding protein. | 0.997 |
ERJ19258.1 | clpB | SSPSH_001867 | SSPSH_001571 | Two-component sensor histidine kinase protein. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.768 |