STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpBPutative carboxyphosphonoenolpyruvate phosphonomutase protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (289 aa)    
Predicted Functional Partners:
prpC
Citrate synthase protein; Belongs to the citrate synthase family.
 0.993
ERJ19269.1
2-methylcitrate dehydratase protein.
 
  
 0.971
gltA
Citrate synthase protein; Belongs to the citrate synthase family.
 0.923
glcB
Malate synthase G protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.902
paaZ
Bifunctional protein PaaZ.
  
 
 0.777
dadA
D-amino acid dehydrogenase small subunit protein.
  
 
 0.731
ERJ18271.1
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.723
ERJ18753.1
methylmalonyl-CoA carboxyltransferase protein.
  
 
  0.718
ERJ17987.1
citryl-CoA lyase protein; Belongs to the HpcH/HpaI aldolase family.
    
 0.715
leuC
3-isopropylmalate dehydratase large subunit protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.705
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.