STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ18929.1Acetolactate synthase I-II-III large subunit protein. (217 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase isozyme 3 small subunit protein.
 
 0.994
ilvC
Ketol-acid reductoisomerase protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.919
ilvD
Dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family.
 
 
 0.850
ilvB2
Acetolactate synthase large subunit biosynthetic type protein.
  
     0.766
ERJ18487.1
Acetolactate synthase I-II-III large subunit protein; Belongs to the TPP enzyme family.
  
     0.766
katE
Catalase HPII protein; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.766
yfiQ
Putative acetyltransferase protein.
   
  0.743
glcD
Glycolate oxidase subunit protein.
    
 0.718
leuD
3-isopropylmalate dehydratase small subunit protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.709
katA
Catalase protein.
   
 0.707
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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