STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase protein; Belongs to the GPI family. (546 aa)    
Predicted Functional Partners:
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.985
tpiA
Triosephosphate isomerase protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.985
pgk
Phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family.
 
 0.983
pykA
Pyruvate kinase protein; Belongs to the pyruvate kinase family.
 
 
 0.978
eno
Enolase protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.972
gapA
Glyceraldehyde 3-phosphate dehydrogenase 1 protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.951
xanB
Xanthan biosynthesis protein XanB; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.907
zwf
Glucose-6-phosphate 1-dehydrogenase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.904
gpmA
23-bisphosphoglycerate-dependent phosphoglycerate mutase protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 
 0.891
pgl
6-phosphogluconolactonase Pgl protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.882
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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