STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (277 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panD
Aspartate 1-decarboxylase protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.989
ERJ18999.1
Deoxyguanosine kinase protein.
 
 0.829
panE
Putative 2-dehydropantoate 2-reductase protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
  
 0.800
ERJ19355.1
2-dehydropantoate 2-reductase protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.763
nadC
Nicotinate-nucleotide pyrophosphorylase carboxylating protein; Belongs to the NadC/ModD family.
     0.707
ERJ19000.1
Poly polymerase protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.687
ilvE
Putative branched-chain amino acid aminotransferase IlvE protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.685
ilvD
Dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family.
     
 0.683
pabC
4-amino-4-deoxychorismate lyase protein.
    
 0.654
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.