STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepAPutative cytosol aminopeptidase protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)    
Predicted Functional Partners:
degQ
Serine endoprotease protein; Belongs to the peptidase S1C family.
  
 
 0.832
holC
DNA polymerase III subunit chi protein.
 
  
 0.823
ERJ18999.1
Deoxyguanosine kinase protein.
    
 0.809
ERJ18848.1
Aminopeptidase N protein.
  
 0.781
gshB
Glutathione synthetase protein; Belongs to the prokaryotic GSH synthase family.
   
 
 0.778
phhC
Aromatic-amino-acid aminotransferase protein.
    
 0.724
nagZ
Beta-hexosaminidase protein.
    
 0.721
gmk
Guanylate kinase protein; Essential for recycling GMP and indirectly, cGMP.
 
  
  0.721
cysM
Cysteine synthase B protein; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.688
glyA
Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.666
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.