STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ18398.1Glutathione S-transferase protein. (241 aa)    
Predicted Functional Partners:
ERJ20162.1
Glutathione S-transferase protein.
  
  
  0.736
tpm
Thiopurine S-methyltransferase protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
       0.664
rpoA
DNA-directed RNA polymerase subunit alpha protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.651
gst
Glutathione S-transferase protein.
     
 0.622
metG
Methionine--tRNA ligase protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
 0.538
proS
Proline--tRNA ligase protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involv [...]
   
  0.535
rpoC
DNA-directed RNA polymerase subunit beta' protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.534
purU1
Formyltetrahydrofolate deformylase protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
 
     0.530
dinB
DNA polymerase IV protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.529
rpoB
DNA-directed RNA polymerase subunit beta protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.517
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.