STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ18228.13-hydroxy-2-methylbutyryl-CoA dehydrogenase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)    
Predicted Functional Partners:
nuoC
NADH-quinone oxidoreductase subunit C-D protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.958
ERJ18531.1
Putative polyketide synthase protein.
  
 0.875
gltB
Glutamate synthase large chain protein.
     
 0.783
ERJ18753.1
methylmalonyl-CoA carboxyltransferase protein.
  
 
 0.674
hisD
Histidinol dehydrogenase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
      0.641
xanB
Xanthan biosynthesis protein XanB; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.628
kdkA
3-deoxy-D-manno-octulosonic acid kinase protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
    
  0.625
metH
Methionine synthase protein.
   
 
  0.616
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.616
ERJ19982.1
Formate dehydrogenase alpha subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
 0.608
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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