node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERJ17769.1 | ERJ18837.1 | SSPSH_003453 | SSPSH_002130 | Exodeoxyribonuclease V alpha subunit protein. | DNA polymerase III subunit epsilon protein. | 0.647 |
ERJ17769.1 | ERJ19260.1 | SSPSH_003453 | SSPSH_001869 | Exodeoxyribonuclease V alpha subunit protein. | ATP-dependent DNA helicase RecQ protein. | 0.480 |
ERJ17769.1 | ada | SSPSH_003453 | SSPSH_002964 | Exodeoxyribonuclease V alpha subunit protein. | O6-methylguanine-DNA methyltransferase protein. | 0.480 |
ERJ17769.1 | dnaN | SSPSH_003453 | SSPSH_000408 | Exodeoxyribonuclease V alpha subunit protein. | DNA polymerase III subunit beta protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.914 |
ERJ17769.1 | polA | SSPSH_003453 | SSPSH_000432 | Exodeoxyribonuclease V alpha subunit protein. | DNA polymerase I protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.537 |
ERJ17769.1 | recB | SSPSH_003453 | SSPSH_001478 | Exodeoxyribonuclease V alpha subunit protein. | Exodeoxyribonuclease V beta subunit protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] | 0.993 |
ERJ17769.1 | recC | SSPSH_003453 | SSPSH_001476 | Exodeoxyribonuclease V alpha subunit protein. | Exodeoxyribonuclease V gamma subunit protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombinatio [...] | 0.991 |
ERJ17769.1 | recQ | SSPSH_003453 | SSPSH_003054 | Exodeoxyribonuclease V alpha subunit protein. | ATP-dependent DNA helicase RecQ protein. | 0.480 |
ERJ17769.1 | topA | SSPSH_003453 | SSPSH_003477 | Exodeoxyribonuclease V alpha subunit protein. | DNA topoisomerase protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DN [...] | 0.606 |
ERJ17769.1 | truB | SSPSH_003453 | SSPSH_002380 | Exodeoxyribonuclease V alpha subunit protein. | tRNA pseudouridine synthase B protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.668 |
ERJ18837.1 | ERJ17769.1 | SSPSH_002130 | SSPSH_003453 | DNA polymerase III subunit epsilon protein. | Exodeoxyribonuclease V alpha subunit protein. | 0.647 |
ERJ18837.1 | ERJ19260.1 | SSPSH_002130 | SSPSH_001869 | DNA polymerase III subunit epsilon protein. | ATP-dependent DNA helicase RecQ protein. | 0.865 |
ERJ18837.1 | ada | SSPSH_002130 | SSPSH_002964 | DNA polymerase III subunit epsilon protein. | O6-methylguanine-DNA methyltransferase protein. | 0.500 |
ERJ18837.1 | dnaN | SSPSH_002130 | SSPSH_000408 | DNA polymerase III subunit epsilon protein. | DNA polymerase III subunit beta protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...] | 0.905 |
ERJ18837.1 | polA | SSPSH_002130 | SSPSH_000432 | DNA polymerase III subunit epsilon protein. | DNA polymerase I protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.976 |
ERJ18837.1 | recQ | SSPSH_002130 | SSPSH_003054 | DNA polymerase III subunit epsilon protein. | ATP-dependent DNA helicase RecQ protein. | 0.836 |
ERJ18837.1 | topA | SSPSH_002130 | SSPSH_003477 | DNA polymerase III subunit epsilon protein. | DNA topoisomerase protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DN [...] | 0.826 |
ERJ18837.1 | truB | SSPSH_002130 | SSPSH_002380 | DNA polymerase III subunit epsilon protein. | tRNA pseudouridine synthase B protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.720 |
ERJ19260.1 | ERJ17769.1 | SSPSH_001869 | SSPSH_003453 | ATP-dependent DNA helicase RecQ protein. | Exodeoxyribonuclease V alpha subunit protein. | 0.480 |
ERJ19260.1 | ERJ18837.1 | SSPSH_001869 | SSPSH_002130 | ATP-dependent DNA helicase RecQ protein. | DNA polymerase III subunit epsilon protein. | 0.865 |