STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa)    
Predicted Functional Partners:
icd
Isocitrate dehydrogenase NADP protein.
  
 0.972
prpC
Citrate synthase protein; Belongs to the citrate synthase family.
  
 0.927
gltA
Citrate synthase protein; Belongs to the citrate synthase family.
  
 0.927
fumC
Fumarate hydratase class II protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.881
ERJ20732.1
NADH dehydrogenase I subunit F protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.879
lpdA
Dihydrolipoyl dehydrogenase protein.
  
 0.837
ERJ18271.1
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 0.827
gapA
Glyceraldehyde 3-phosphate dehydrogenase 1 protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.825
pykA
Pyruvate kinase protein; Belongs to the pyruvate kinase family.
  
 0.823
sdhB
Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.815
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.