STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ17607.13-carboxy-ciscis-muconate cycloisomerase protein. (445 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.992
pcaG
Protocatechuate 34-dioxygenase alpha subunit protein.
 
 
 0.979
pcaH
Protocatechuate 34-dioxygenase beta subunit protein.
 
 
 0.978
pcaC
4-carboxymuconolactone decarboxylase protein.
 
 0.972
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase protein; Belongs to the SAICAR synthetase family.
  
 0.962
purA
Adenylosuccinate synthetase protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.959
purH
Bifunctional purine biosynthesis protein PurH.
  
 0.959
purD
Phosphoribosylamine--glycine ligase protein; Belongs to the GARS family.
  
 0.940
purE
N5-carboxyaminoimidazole ribonucleotide mutase protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
 
 0.921
purN
Phosphoribosylaminoimidazole synthetase protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.917
Your Current Organism:
Salinisphaera shabanensis
NCBI taxonomy Id: 1033802
Other names: S. shabanensis E1L3A, Salinisphaera shabanensis E1L3A, Salinisphaera shabanensis str. E1L3A, Salinisphaera shabanensis strain E1L3A
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