node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERJ12827.1 | ERJ13828.1 | HLPCO_001167 | HLPCO_000494 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Rhomboid domain containing protein. | 0.615 |
ERJ12827.1 | eno | HLPCO_001167 | HLPCO_000955 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.563 |
ERJ12827.1 | glyA | HLPCO_001167 | HLPCO_002590 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.583 |
ERJ12827.1 | pfkA | HLPCO_001167 | HLPCO_002979 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.581 |
ERJ12827.1 | pgi | HLPCO_001167 | HLPCO_000027 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Glucose-6-phosphate isomerase protein; Belongs to the GPI family. | 0.588 |
ERJ12827.1 | pgk | HLPCO_001167 | HLPCO_001304 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family. | 0.563 |
ERJ12827.1 | rpe | HLPCO_001167 | HLPCO_000079 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Ribulose-phosphate 3-epimerase protein; Belongs to the ribulose-phosphate 3-epimerase family. | 0.587 |
ERJ12827.1 | tal | HLPCO_001167 | HLPCO_002437 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Putative transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.597 |
ERJ12827.1 | tkt2 | HLPCO_001167 | HLPCO_000410 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Transketolase Carbohydrate transport protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.570 |
ERJ12827.1 | zwf | HLPCO_001167 | HLPCO_002041 | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | Glucose-6-phosphate 1-dehydrogenase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.568 |
ERJ13828.1 | ERJ12827.1 | HLPCO_000494 | HLPCO_001167 | Rhomboid domain containing protein. | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | 0.615 |
eno | ERJ12827.1 | HLPCO_000955 | HLPCO_001167 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate mutase protein; Belongs to the phosphoglycerate mutase family. | 0.563 |
eno | glyA | HLPCO_000955 | HLPCO_002590 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.469 |
eno | pfkA | HLPCO_000955 | HLPCO_002979 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.790 |
eno | pgi | HLPCO_000955 | HLPCO_000027 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate isomerase protein; Belongs to the GPI family. | 0.916 |
eno | pgk | HLPCO_000955 | HLPCO_001304 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoglycerate kinase protein; Belongs to the phosphoglycerate kinase family. | 0.986 |
eno | rpe | HLPCO_000955 | HLPCO_000079 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Ribulose-phosphate 3-epimerase protein; Belongs to the ribulose-phosphate 3-epimerase family. | 0.778 |
eno | tal | HLPCO_000955 | HLPCO_002437 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Putative transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.816 |
eno | tkt2 | HLPCO_000955 | HLPCO_000410 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Transketolase Carbohydrate transport protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.879 |
eno | zwf | HLPCO_000955 | HLPCO_002041 | Enolase Carbohydrate transport protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Glucose-6-phosphate 1-dehydrogenase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.691 |