STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ12570.1Serine-pyruvate transaminase protein. (360 aa)    
Predicted Functional Partners:
ERJ12012.1
D-3-phosphoglycerate dehydrogenase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.767
ERJ13551.1
Glycerate dehydrogenase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.742
ERJ11628.1
Amidase family protein.
 
  0.728
glyA
Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.727
yvdM
Putative phosphatase-phosphohexomutase ral function prediction only protein.
    
 0.715
gcvT
Glycine cleavage system T protein Amino acid transport; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.708
ERJ11586.1
Threonine aldolase protein.
    
 0.676
adhE
Aldehyde-alcohol dehydrogenase protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.674
alaS
Alanine--tRNA ligase protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
  
 0.672
metG
Methionine--tRNA ligase protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
      0.671
Your Current Organism:
Haloplasma contractile
NCBI taxonomy Id: 1033810
Other names: H. contractile SSD-17B, Haloplasma contractile SSD-17B, Haloplasma contractile str. SSD-17B, Haloplasma contractile strain SSD-17B
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.