STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tadAtRNA-specific adenosine deaminase protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (172 aa)    
Predicted Functional Partners:
hisI
Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.
   
  
 0.960
tilS
Bifunctional protein TilS-HprT; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
 
 0.948
ERJ13148.1
Glycerate kinase protein; Belongs to the glycerate kinase type-1 family.
 
 
    0.901
ung
Uracil-DNA glycosylase protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 
 0.818
ribBA
GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.770
ERJ12431.1
Phosphoribosyl transferase domain protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.749
ERJ13595.1
DNA-3-methyladenine glycosylase protein; Belongs to the DNA glycosylase MPG family.
    
 0.712
thyA2
Thymidylate synthase 2 protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.710
exoA
Exodeoxyribonuclease protein.
   
 
 0.684
upp
Uracil phosphoribosyltransferase protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
 0.675
Your Current Organism:
Haloplasma contractile
NCBI taxonomy Id: 1033810
Other names: H. contractile SSD-17B, Haloplasma contractile SSD-17B, Haloplasma contractile str. SSD-17B, Haloplasma contractile strain SSD-17B
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