node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ERJ11985.1 | ERJ11986.1 | HLPCO_001899 | HLPCO_001900 | Phosphoglycerate mutase protein. | Phenazine biosynthesis protein PhzF family protein. | 0.660 |
ERJ11985.1 | ERJ13828.1 | HLPCO_001899 | HLPCO_000494 | Phosphoglycerate mutase protein. | Rhomboid domain containing protein. | 0.615 |
ERJ11985.1 | dagK | HLPCO_001899 | HLPCO_000735 | Phosphoglycerate mutase protein. | Diacylglycerol kinase protein. | 0.585 |
ERJ11985.1 | glyA | HLPCO_001899 | HLPCO_002590 | Phosphoglycerate mutase protein. | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.583 |
ERJ11985.1 | pfkA | HLPCO_001899 | HLPCO_002979 | Phosphoglycerate mutase protein. | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.581 |
ERJ11985.1 | pgi | HLPCO_001899 | HLPCO_000027 | Phosphoglycerate mutase protein. | Glucose-6-phosphate isomerase protein; Belongs to the GPI family. | 0.588 |
ERJ11985.1 | rpe | HLPCO_001899 | HLPCO_000079 | Phosphoglycerate mutase protein. | Ribulose-phosphate 3-epimerase protein; Belongs to the ribulose-phosphate 3-epimerase family. | 0.587 |
ERJ11985.1 | tal | HLPCO_001899 | HLPCO_002437 | Phosphoglycerate mutase protein. | Putative transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.597 |
ERJ11985.1 | tkt2 | HLPCO_001899 | HLPCO_000410 | Phosphoglycerate mutase protein. | Transketolase Carbohydrate transport protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.570 |
ERJ11985.1 | zwf | HLPCO_001899 | HLPCO_002041 | Phosphoglycerate mutase protein. | Glucose-6-phosphate 1-dehydrogenase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.568 |
ERJ11986.1 | ERJ11985.1 | HLPCO_001900 | HLPCO_001899 | Phenazine biosynthesis protein PhzF family protein. | Phosphoglycerate mutase protein. | 0.660 |
ERJ13828.1 | ERJ11985.1 | HLPCO_000494 | HLPCO_001899 | Rhomboid domain containing protein. | Phosphoglycerate mutase protein. | 0.615 |
dagK | ERJ11985.1 | HLPCO_000735 | HLPCO_001899 | Diacylglycerol kinase protein. | Phosphoglycerate mutase protein. | 0.585 |
glyA | ERJ11985.1 | HLPCO_002590 | HLPCO_001899 | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoglycerate mutase protein. | 0.583 |
glyA | tal | HLPCO_002590 | HLPCO_002437 | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.407 |
glyA | tkt2 | HLPCO_002590 | HLPCO_000410 | Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Transketolase Carbohydrate transport protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.429 |
pfkA | ERJ11985.1 | HLPCO_002979 | HLPCO_001899 | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Phosphoglycerate mutase protein. | 0.581 |
pfkA | pgi | HLPCO_002979 | HLPCO_000027 | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Glucose-6-phosphate isomerase protein; Belongs to the GPI family. | 0.956 |
pfkA | rpe | HLPCO_002979 | HLPCO_000079 | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Ribulose-phosphate 3-epimerase protein; Belongs to the ribulose-phosphate 3-epimerase family. | 0.691 |
pfkA | tal | HLPCO_002979 | HLPCO_002437 | 6-phosphofructokinase Carbohydrate transport protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | Putative transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.699 |