STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
WANG_17693-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (409 aa)    
Predicted Functional Partners:
WANG_1767
S-malonyltransferase.
 0.999
WANG_1770
Acetyl-CoA biotin carboxyl carrier; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.999
WANG_1775
Enoyl-[acyl-carrier-protein] reductase [NADH].
 
 
 0.999
fabZ
(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.998
fabH
3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.998
WANG_1768
Dehydrogenase.
 0.998
acpP-2
Acyl carrier protein 2; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.997
WANG_1772
Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.994
WANG_1774
Acetyl-CoA carboxylase alpha subunit.
  
  
 0.994
WANG_1771
Carrier protein.
 
 
 0.988
Your Current Organism:
Lactobacillus kefiranofaciens
NCBI taxonomy Id: 1033837
Other names: L. kefiranofaciens ZW3, Lactobacillus kefiranofaciens ZW3, Lactobacillus kefiranofaciens str. ZW3, Lactobacillus kefiranofaciens strain ZW3
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