STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase (NADP+); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa)    
Predicted Functional Partners:
acnB
Aconitate hydratase; Carbohydrate metabolism; tricarboxylic acid cycle.
  
 
 0.978
sucA
Oxoglutarate dehydrogenase (succinyl-transferring).
   
 
 0.974
fumA
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.954
gltA
Citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.918
gdhA
Glutamate dehydrogenase (NADP+); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.912
gltB
Probable glutamate synthase (NADPH) large subunit.
    
 0.904
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.895
sucC
Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.875
gcvP
Glycine dehydrogenase (decarboxylating); Belongs to the GcvP family.
   
  
 0.865
aspC1
Probable aspartate transaminase AspC1.
   
 0.831
Your Current Organism:
Flavobacterium branchiophilum
NCBI taxonomy Id: 1034807
Other names: F. branchiophilum FL-15, Flavobacterium branchiophilum FL-15, Flavobacterium branchiophilum str. FL-15, Flavobacterium branchiophilum strain FL-15
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.