STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1-alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (372 aa)    
Predicted Functional Partners:
GIG_01438
COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.
 0.999
GIG_00712
COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
 
 0.998
GIG_01433
Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
 0.998
GIG_01950
COG0095 Lipoate-protein ligase A.
  
 
 0.867
GIG_03427
COG0021 Transketolase; Belongs to the transketolase family.
  
 
 0.867
GIG_00687
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
 0.865
GIG_03327
Fructose-1,6-bisphosphate aldolase, class II; COG0191 Fructose/tagatose bisphosphate aldolase.
    
 0.864
GIG_03547
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.862
GIG_03158
Hypothetical protein; COG0166 Glucose-6-phosphate isomerase.
    
 0.836
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.836
Your Current Organism:
Mycoplasma anatis
NCBI taxonomy Id: 1034808
Other names: M. anatis 1340, Mycoplasma anatis 1340, Mycoplasma anatis ATCC 25524
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