STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIG_02498COG0286 Type I restriction-modification system methyltransferase subunit. (525 aa)    
Predicted Functional Partners:
GIG_00530
Type I restriction-modification system, helicase subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 0.998
GIG_02493
Anti-codon nuclease masking agent (prrB); COG0732 Restriction endonuclease S subunits.
 
 
 0.994
GIG_01468
Type I restriction system specificity protein; COG0732 Restriction endonuclease S subunits.
 
 
 0.970
GIG_00535
Type I restriction enzyme specificity protein; COG0732 Restriction endonuclease S subunits.
  
 
 0.891
GIG_03068
Restriction modification system DNA specificity domain protein; COG0732 Restriction endonuclease S subunits.
  
 
 0.891
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.655
GIG_02463
Hypothetical protein.
       0.596
GIG_02468
Hypothetical protein; COG0629 Single-stranded DNA-binding protein.
       0.596
GIG_02473
Hypothetical protein.
       0.596
GIG_02478
Hypothetical protein.
       0.596
Your Current Organism:
Mycoplasma anatis
NCBI taxonomy Id: 1034808
Other names: M. anatis 1340, Mycoplasma anatis 1340, Mycoplasma anatis ATCC 25524
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.