node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GIG_00632 | GIG_00712 | GIG_00632 | GIG_00712 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.864 |
GIG_00632 | GIG_03512 | GIG_00632 | GIG_03512 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | COG0492 Thioredoxin reductase. | 0.954 |
GIG_00632 | pheT | GIG_00632 | GIG_02733 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.413 |
GIG_00712 | GIG_00632 | GIG_00712 | GIG_00632 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.864 |
GIG_00712 | GIG_01409 | GIG_00712 | GIG_01409 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Putative thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. | 0.864 |
GIG_00712 | GIG_02251 | GIG_00712 | GIG_02251 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | COG0143 Methionyl-tRNA synthetase. | 0.686 |
GIG_00712 | GIG_03512 | GIG_00712 | GIG_03512 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | COG0492 Thioredoxin reductase. | 0.833 |
GIG_00712 | GIG_03814 | GIG_00712 | GIG_03814 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | NADH oxidase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.846 |
GIG_00712 | glyA | GIG_00712 | GIG_02728 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.938 |
GIG_00712 | pheT | GIG_00712 | GIG_02733 | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.650 |
GIG_01409 | GIG_00712 | GIG_01409 | GIG_00712 | Putative thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.864 |
GIG_01409 | GIG_03512 | GIG_01409 | GIG_03512 | Putative thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. | COG0492 Thioredoxin reductase. | 0.943 |
GIG_01409 | pheT | GIG_01409 | GIG_02733 | Putative thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins. | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.413 |
GIG_01513 | GIG_03512 | GIG_01513 | GIG_03512 | Aminotransferase, class V; COG0520 Selenocysteine lyase. | COG0492 Thioredoxin reductase. | 0.836 |
GIG_01513 | glyA | GIG_01513 | GIG_02728 | Aminotransferase, class V; COG0520 Selenocysteine lyase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.607 |
GIG_01513 | pheT | GIG_01513 | GIG_02733 | Aminotransferase, class V; COG0520 Selenocysteine lyase. | phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.670 |
GIG_02251 | GIG_00712 | GIG_02251 | GIG_00712 | COG0143 Methionyl-tRNA synthetase. | COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. | 0.686 |
GIG_02251 | GIG_03512 | GIG_02251 | GIG_03512 | COG0143 Methionyl-tRNA synthetase. | COG0492 Thioredoxin reductase. | 0.584 |
GIG_02251 | GIG_03964 | GIG_02251 | GIG_03964 | COG0143 Methionyl-tRNA synthetase. | COG0342 Preprotein translocase subunit SecD. | 0.852 |
GIG_02251 | glyA | GIG_02251 | GIG_02728 | COG0143 Methionyl-tRNA synthetase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.558 |