STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C0W2D7_9ACTOUnannotated protein. (458 aa)    
Predicted Functional Partners:
C0W2D6_9ACTO
Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.898
ftsE
Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division.
 
   
 0.874
smpB
Unannotated protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.711
C0W567_9ACTO
Unannotated protein.
  
     0.619
C0W4W8_9ACTO
Unannotated protein.
  
     0.596
C0W2D4_9ACTO
Unannotated protein.
       0.518
C0W8N4_9ACTO
Unannotated protein.
  
   
0.446
murE
Unannotated protein; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
 
  
  0.431
murF
Unannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
  0.414
Your Current Organism:
Actinomyces urogenitalis
NCBI taxonomy Id: 103621
Other names: A. urogenitalis, Actinomyces sp. CCUG 28744, Actinomyces sp. CCUG 42029, Actinomyces urogenitalis Nikolaitchouk et al. 2000 emend. Nouioui et al. 2018, CCUG 38702, CIP 106421, DSM 15434
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