STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK61066.1DNA topoisomerase III; COG0550 Topoisomerase IA. (907 aa)    
Predicted Functional Partners:
AFK63542.1
COG0514 Superfamily II DNA helicase.
 
 0.997
AFK63588.1
COG5531 SWIB-domain-containing proteins implicated in chromatin remodeling.
 
  
   0.905
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.769
AFK62958.1
Hypothetical protein.
  
   
 0.728
AFK61065.1
COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.717
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.708
AFK61064.1
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
       0.700
AFK63519.1
Thioredoxin-like protein; COG0526 Thiol-disulfide isomerase and thioredoxins.
 
  
 0.698
AFK64130.1
COG0629 Single-stranded DNA-binding protein.
  
 
 0.642
AFK64359.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.642
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.