node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK63832.1 | AFK64263.1 | TKWG_20385 | TKWG_23330 | Phosphoglucomutase; COG1109 Phosphomannomutase. | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.988 |
AFK63832.1 | glmS | TKWG_20385 | TKWG_02925 | Phosphoglucomutase; COG1109 Phosphomannomutase. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.641 |
AFK63832.1 | murE | TKWG_20385 | TKWG_18715 | Phosphoglucomutase; COG1109 Phosphomannomutase. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.567 |
AFK64263.1 | AFK63832.1 | TKWG_23330 | TKWG_20385 | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucomutase; COG1109 Phosphomannomutase. | 0.988 |
AFK64263.1 | glmM | TKWG_23330 | TKWG_08525 | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.644 |
AFK64263.1 | glmS | TKWG_23330 | TKWG_02925 | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.927 |
AFK64263.1 | glmU | TKWG_23330 | TKWG_02960 | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.438 |
carA | carB | TKWG_08455 | TKWG_08460 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.999 |
carA | glmS | TKWG_08455 | TKWG_02925 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.916 |
carA | gltD | TKWG_08455 | TKWG_03095 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.911 |
carA | guaA | TKWG_08455 | TKWG_12350 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.768 |
carA | purF | TKWG_08455 | TKWG_11540 | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.971 |
carB | carA | TKWG_08460 | TKWG_08455 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.999 |
carB | glmS | TKWG_08460 | TKWG_02925 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.941 |
carB | gltD | TKWG_08460 | TKWG_03095 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.924 |
carB | guaA | TKWG_08460 | TKWG_12350 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.891 |
carB | murE | TKWG_08460 | TKWG_18715 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.441 |
carB | purF | TKWG_08460 | TKWG_11540 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.982 |
glmM | AFK64263.1 | TKWG_08525 | TKWG_23330 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Mannose-1-phosphate guanylyltransferase-mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.644 |
glmM | glmS | TKWG_08525 | TKWG_02925 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.964 |