node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK61222.1 | AFK61223.1 | TKWG_03130 | TKWG_03135 | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | COG1131 ABC-type multidrug transport system, ATPase component. | 0.734 |
AFK61222.1 | AFK61224.1 | TKWG_03130 | TKWG_03140 | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | 0.757 |
AFK61222.1 | AFK61225.1 | TKWG_03130 | TKWG_03145 | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | BolA-like protein; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | 0.709 |
AFK61222.1 | hisG | TKWG_03130 | TKWG_03155 | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.642 |
AFK61222.1 | murA | TKWG_03130 | TKWG_03150 | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.691 |
AFK61223.1 | AFK61222.1 | TKWG_03135 | TKWG_03130 | COG1131 ABC-type multidrug transport system, ATPase component. | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | 0.734 |
AFK61223.1 | AFK61224.1 | TKWG_03135 | TKWG_03140 | COG1131 ABC-type multidrug transport system, ATPase component. | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | 0.979 |
AFK61223.1 | AFK61225.1 | TKWG_03135 | TKWG_03145 | COG1131 ABC-type multidrug transport system, ATPase component. | BolA-like protein; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | 0.845 |
AFK61223.1 | hisB | TKWG_03135 | TKWG_03165 | COG1131 ABC-type multidrug transport system, ATPase component. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.497 |
AFK61223.1 | hisD | TKWG_03135 | TKWG_03160 | COG1131 ABC-type multidrug transport system, ATPase component. | Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.626 |
AFK61223.1 | hisG | TKWG_03135 | TKWG_03155 | COG1131 ABC-type multidrug transport system, ATPase component. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.799 |
AFK61223.1 | hisH | TKWG_03135 | TKWG_03170 | COG1131 ABC-type multidrug transport system, ATPase component. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.470 |
AFK61223.1 | murA | TKWG_03135 | TKWG_03150 | COG1131 ABC-type multidrug transport system, ATPase component. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.845 |
AFK61224.1 | AFK61222.1 | TKWG_03140 | TKWG_03130 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | Putative ABC transporter; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component. | 0.757 |
AFK61224.1 | AFK61223.1 | TKWG_03140 | TKWG_03135 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | COG1131 ABC-type multidrug transport system, ATPase component. | 0.979 |
AFK61224.1 | AFK61225.1 | TKWG_03140 | TKWG_03145 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | BolA-like protein; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family. | 0.868 |
AFK61224.1 | hisB | TKWG_03140 | TKWG_03165 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | COG0131 Imidazoleglycerol-phosphate dehydratase. | 0.503 |
AFK61224.1 | hisD | TKWG_03140 | TKWG_03160 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.592 |
AFK61224.1 | hisG | TKWG_03140 | TKWG_03155 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.798 |
AFK61224.1 | hisH | TKWG_03140 | TKWG_03170 | ABC transporter permease; COG0842 ABC-type multidrug transport system, permease component. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.470 |