node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK60962.1 | aroE | TKWG_01470 | TKWG_06250 | COG4993 Glucose dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.900 |
AFK60962.1 | aroK | TKWG_01470 | TKWG_23910 | COG4993 Glucose dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.900 |
AFK60962.1 | aroQ | TKWG_01470 | TKWG_06280 | COG4993 Glucose dehydrogenase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.900 |
AFK61281.1 | AFK62373.1 | TKWG_03460 | TKWG_10585 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.507 |
AFK61281.1 | AFK63648.1 | TKWG_03460 | TKWG_19155 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.999 |
AFK61281.1 | aroC | TKWG_03460 | TKWG_14395 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.966 |
AFK61281.1 | aroE | TKWG_03460 | TKWG_06250 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.778 |
AFK61281.1 | aroK | TKWG_03460 | TKWG_23910 | COG0512 Anthranilate/para-aminobenzoate synthases component II. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.591 |
AFK61706.1 | AFK61707.1 | TKWG_06255 | TKWG_06260 | COG0557 Exoribonuclease R. | Hypothetical protein; COG3150 Predicted esterase. | 0.829 |
AFK61706.1 | AFK62373.1 | TKWG_06255 | TKWG_10585 | COG0557 Exoribonuclease R. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.541 |
AFK61706.1 | aroE | TKWG_06255 | TKWG_06250 | COG0557 Exoribonuclease R. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.935 |
AFK61707.1 | AFK61706.1 | TKWG_06260 | TKWG_06255 | Hypothetical protein; COG3150 Predicted esterase. | COG0557 Exoribonuclease R. | 0.829 |
AFK61707.1 | aroE | TKWG_06260 | TKWG_06250 | Hypothetical protein; COG3150 Predicted esterase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.763 |
AFK62373.1 | AFK61281.1 | TKWG_10585 | TKWG_03460 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.507 |
AFK62373.1 | AFK61706.1 | TKWG_10585 | TKWG_06255 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | COG0557 Exoribonuclease R. | 0.541 |
AFK62373.1 | AFK63648.1 | TKWG_10585 | TKWG_19155 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | COG0147 Anthranilate/para-aminobenzoate synthases component I. | 0.633 |
AFK62373.1 | aroC | TKWG_10585 | TKWG_14395 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
AFK62373.1 | aroE | TKWG_10585 | TKWG_06250 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.821 |
AFK62373.1 | aroK | TKWG_10585 | TKWG_23910 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.997 |
AFK63648.1 | AFK61281.1 | TKWG_19155 | TKWG_03460 | COG0147 Anthranilate/para-aminobenzoate synthases component I. | COG0512 Anthranilate/para-aminobenzoate synthases component II. | 0.999 |