STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (211 aa)    
Predicted Functional Partners:
dnaE2-2
COG0587 DNA polymerase III, alpha subunit.
     0.971
AFK61842.1
COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
     0.967
AFK61840.1
COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair.
  
  
 0.869
AFK61837.1
Hypothetical protein; COG0468 RecA/RadA recombinase.
 
  
 0.863
holA
COG1466 DNA polymerase III, delta subunit.
  
 
 0.707
AFK62054.1
COG2812 DNA polymerase III, gamma/tau subunits.
  
 
 0.688
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
   
 
 0.677
AFK60740.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.673
AFK62280.1
Hypothetical protein; COG2927 DNA polymerase III, chi subunit.
   
 
 0.673
AFK62546.1
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
    
 
 0.673
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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