STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK61998.1ChaC-like family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (144 aa)    
Predicted Functional Partners:
gshB
COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
    
 0.908
AFK64311.1
5-oxoprolinase; COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit.
     
 0.908
AFK61140.1
COG0405 Gamma-glutamyltransferase.
   
 
 0.905
pepA
Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.905
AFK62876.1
COG0405 Gamma-glutamyltransferase.
   
 
 0.905
AFK64420.1
COG0405 Gamma-glutamyltransferase.
   
 
 0.905
AFK61128.1
Glutaredoxin family protein; COG0678 Peroxiredoxin.
     
 0.903
AFK62553.1
COG0386 Glutathione peroxidase; Belongs to the glutathione peroxidase family.
     
 0.903
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
    
  0.902
AFK62879.1
COG0625 Glutathione S-transferase; Belongs to the GST superfamily.
     
 0.901
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
Server load: low (24%) [HD]