STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK62054.1COG2812 DNA polymerase III, gamma/tau subunits. (803 aa)    
Predicted Functional Partners:
AFK62546.1
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
 
 
0.997
AFK60740.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.996
holA
COG1466 DNA polymerase III, delta subunit.
 
 
 0.996
AFK62280.1
Hypothetical protein; COG2927 DNA polymerase III, chi subunit.
    
 0.995
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
 0.992
dnaE
COG0587 DNA polymerase III, alpha subunit.
 
 0.972
AFK62213.1
COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.
   
 0.968
AFK62055.1
Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
 
  
 0.945
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
 0.907
AFK64130.1
COG0629 Single-stranded DNA-binding protein.
   
 
 0.808
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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