node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK61304.1 | AFK61412.1 | TKWG_03595 | TKWG_04365 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.916 |
AFK61304.1 | AFK61966.1 | TKWG_03595 | TKWG_07745 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | ADP-heptose--LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.562 |
AFK61304.1 | AFK62377.1 | TKWG_03595 | TKWG_10625 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | D-beta-d-heptose 7-phosphate kinase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. | 0.690 |
AFK61304.1 | AFK63086.1 | TKWG_03595 | TKWG_15420 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | COG0859 ADP-heptose:LPS heptosyltransferase. | 0.421 |
AFK61304.1 | gmhA | TKWG_03595 | TKWG_03535 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.811 |
AFK61304.1 | lpxB | TKWG_03595 | TKWG_11660 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.968 |
AFK61304.1 | lpxK | TKWG_03595 | TKWG_15030 | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.967 |
AFK61412.1 | AFK61304.1 | TKWG_04365 | TKWG_03595 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.916 |
AFK61412.1 | AFK61966.1 | TKWG_04365 | TKWG_07745 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | ADP-heptose--LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.431 |
AFK61412.1 | AFK62377.1 | TKWG_04365 | TKWG_10625 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | D-beta-d-heptose 7-phosphate kinase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. | 0.602 |
AFK61412.1 | AFK63086.1 | TKWG_04365 | TKWG_15420 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | COG0859 ADP-heptose:LPS heptosyltransferase. | 0.966 |
AFK61412.1 | gmhA | TKWG_04365 | TKWG_03535 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.775 |
AFK61412.1 | lpxB | TKWG_04365 | TKWG_11660 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.947 |
AFK61412.1 | lpxK | TKWG_04365 | TKWG_15030 | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.994 |
AFK61964.1 | AFK61966.1 | TKWG_07735 | TKWG_07745 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | ADP-heptose--LPS heptosyltransferase II; COG0859 ADP-heptose:LPS heptosyltransferase. | 0.961 |
AFK61964.1 | AFK62027.1 | TKWG_07735 | TKWG_08190 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | D,D-heptose 1,7-bisphosphate phosphatase; COG0241 Histidinol phosphatase and related phosphatases. | 0.917 |
AFK61964.1 | AFK62377.1 | TKWG_07735 | TKWG_10625 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | D-beta-d-heptose 7-phosphate kinase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase. | 0.980 |
AFK61964.1 | AFK63086.1 | TKWG_07735 | TKWG_15420 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | COG0859 ADP-heptose:LPS heptosyltransferase. | 0.449 |
AFK61964.1 | gmhA | TKWG_07735 | TKWG_03535 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.992 |
AFK61964.1 | hldD | TKWG_07735 | TKWG_10630 | Hydrolase, HAD-superfamily, subfamily IIIA; COG0241 Histidinol phosphatase and related phosphatases. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.456 |