STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK62507.1Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (434 aa)    
Predicted Functional Partners:
AFK62069.1
COG0294 Dihydropteroate synthase and related enzymes.
 
 0.997
AFK63845.1
Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.929
AFK62034.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 0.799
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.795
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.736
AFK63017.1
Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.
 
 
 
 0.723
accD
acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
  
 0.713
AFK62508.1
COG3087 Cell division protein.
       0.701
AFK62068.1
COG0294 Dihydropteroate synthase and related enzymes.
 
  
 0.692
AFK64187.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.661
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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