node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK62515.1 | dapD | TKWG_11565 | TKWG_14265 | MarC family integral membrane family protein 2; COG2095 Multiple antibiotic transporter. | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.544 |
AFK62930.1 | argD | TKWG_14260 | TKWG_02125 | Succinyldiaminopimelate transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.914 |
AFK62930.1 | dapD | TKWG_14260 | TKWG_14265 | Succinyldiaminopimelate transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.977 |
AFK62930.1 | dapE | TKWG_14260 | TKWG_14270 | Succinyldiaminopimelate transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.960 |
AFK62930.1 | prmB | TKWG_14260 | TKWG_14275 | Succinyldiaminopimelate transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.424 |
AFK63464.1 | dapA | TKWG_17890 | TKWG_17265 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.987 |
AFK63464.1 | dapD | TKWG_17890 | TKWG_14265 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.962 |
AFK63464.1 | murE | TKWG_17890 | TKWG_18715 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.472 |
argD | AFK62930.1 | TKWG_02125 | TKWG_14260 | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Succinyldiaminopimelate transaminase; COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.914 |
argD | dapA | TKWG_02125 | TKWG_17265 | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.511 |
argD | dapD | TKWG_02125 | TKWG_14265 | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.926 |
argD | dapE | TKWG_02125 | TKWG_14270 | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.924 |
argD | guaA | TKWG_02125 | TKWG_12350 | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.605 |
dapA | AFK63464.1 | TKWG_17265 | TKWG_17890 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | 0.987 |
dapA | argD | TKWG_17265 | TKWG_02125 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.511 |
dapA | dapD | TKWG_17265 | TKWG_14265 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | 0.632 |
dapA | dapE | TKWG_17265 | TKWG_14270 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.443 |
dapA | guaA | TKWG_17265 | TKWG_12350 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.408 |
dapA | murE | TKWG_17265 | TKWG_18715 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.425 |
dapD | AFK62515.1 | TKWG_14265 | TKWG_11565 | COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. | MarC family integral membrane family protein 2; COG2095 Multiple antibiotic transporter. | 0.544 |