STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK63845.1Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (186 aa)    
Predicted Functional Partners:
thyA
COG0207 Thymidylate synthase.
  
 0.997
AFK63843.1
COG0207 Thymidylate synthase.
 
  
 0.971
AFK62507.1
Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.
     
 0.929
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).
    
 0.921
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
    
 0.912
AFK63016.1
COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN.
   
 
 0.911
phhA
COG3186 Phenylalanine-4-hydroxylase.
     
 0.903
AFK62002.1
4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.
    
 0.751
AFK63842.1
COG1765 Predicted redox protein, regulator of disulfide bond formation.
  
    0.675
AFK64114.1
Hypothetical protein.
      0.640
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.