STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK63926.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent). (342 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.978
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.968
AFK64230.1
COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.
  
 
 0.968
AFK61268.1
COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.949
AFK63927.1
Hypothetical protein.
  
 0.947
metG
methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.907
AFK63116.1
COG0460 Homoserine dehydrogenase.
  
 
 0.903
AFK61400.1
COG1956 GAF domain-containing protein.
     
  0.900
AFK61401.1
COG1956 GAF domain-containing protein.
     
  0.900
AFK62898.1
COG0031 Cysteine synthase.
   
 
 0.837
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.