node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFK60813.1 | AFK63212.1 | TKWG_00475 | TKWG_16295 | Cytoplasmic membrane protein. | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | 0.460 |
AFK60813.1 | queC | TKWG_00475 | TKWG_22295 | Cytoplasmic membrane protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.492 |
AFK62422.1 | queC | TKWG_10940 | TKWG_22295 | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.402 |
AFK63212.1 | AFK60813.1 | TKWG_16295 | TKWG_00475 | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | Cytoplasmic membrane protein. | 0.460 |
AFK63212.1 | AFK63213.1 | TKWG_16295 | TKWG_16300 | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | Queuosine biosynthesis protein QueD; COG0720 6-pyruvoyl-tetrahydropterin synthase. | 0.888 |
AFK63212.1 | queA | TKWG_16295 | TKWG_07115 | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.494 |
AFK63212.1 | queC | TKWG_16295 | TKWG_22295 | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.970 |
AFK63212.1 | queF | TKWG_16295 | TKWG_22855 | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.922 |
AFK63213.1 | AFK63212.1 | TKWG_16300 | TKWG_16295 | Queuosine biosynthesis protein QueD; COG0720 6-pyruvoyl-tetrahydropterin synthase. | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | 0.888 |
AFK63213.1 | queC | TKWG_16300 | TKWG_22295 | Queuosine biosynthesis protein QueD; COG0720 6-pyruvoyl-tetrahydropterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.916 |
AFK63213.1 | queF | TKWG_16300 | TKWG_22855 | Queuosine biosynthesis protein QueD; COG0720 6-pyruvoyl-tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.874 |
AFK64106.1 | queC | TKWG_22290 | TKWG_22295 | COG0583 Transcriptional regulator. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.574 |
mnmA | queC | TKWG_10355 | TKWG_22295 | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.504 |
mnmA | queF | TKWG_10355 | TKWG_22855 | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.505 |
queA | AFK63212.1 | TKWG_07115 | TKWG_16295 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | 0.494 |
queA | queC | TKWG_07115 | TKWG_22295 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.590 |
queA | queF | TKWG_07115 | TKWG_22855 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.697 |
queC | AFK60813.1 | TKWG_22295 | TKWG_00475 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Cytoplasmic membrane protein. | 0.492 |
queC | AFK62422.1 | TKWG_22295 | TKWG_10940 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. | 0.402 |
queC | AFK63212.1 | TKWG_22295 | TKWG_16295 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM superfamily protein 3; COG0602 Organic radical activating enzymes. | 0.970 |