STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFK64176.1COG0789 Predicted transcriptional regulators. (158 aa)    
Predicted Functional Partners:
AFK64177.1
COG2217 Cation transport ATPase.
  
 0.883
AFK64178.1
Heavy metal translocating P-type ATPase; COG2217 Cation transport ATPase.
 
  
 0.836
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.629
AFK62079.1
Heavy metal translocating P-type ATPase; COG2217 Cation transport ATPase.
  
 0.498
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.488
AFK64216.1
COG2214 DnaJ-class molecular chaperone.
  
 
 0.488
AFK64217.1
COG2214 DnaJ-class molecular chaperone.
  
 
 0.488
AFK62081.1
Heavy metal translocating P-type ATPase; COG2217 Cation transport ATPase.
  
 0.462
AFK64175.1
COG1960 Acyl-CoA dehydrogenases.
  
    0.440
AFK62478.1
COG0174 Glutamine synthetase.
  
 
 0.425
Your Current Organism:
Advenella kashmirensis WT001
NCBI taxonomy Id: 1036672
Other names: A. kashmirensis WT001, Advenella kashmirensis str. WT001, Advenella kashmirensis strain WT001, Tetrathiobacter kashmirensis WT001
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