node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
all3540 | alr1343 | gene:10495581 | gene:10493358 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
all3540 | alr3573 | gene:10495581 | gene:10495614 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.423 |
all3540 | alr4129 | gene:10495581 | gene:10496177 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.423 |
all3540 | asr1344 | gene:10495581 | gene:10493359 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | ORF_ID:asr1344; hypothetical protein. | 0.811 |
all3540 | moeB | gene:10495581 | gene:10494941 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | Molybdopterin biosynthesis protein; ORF_ID:all2906; moeB gene product. | 0.728 |
all3540 | thiC | gene:10495581 | gene:10492996 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.995 |
all3540 | thiG | gene:10495581 | gene:10495559 | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | Thiamin biosynthesis protein; Catalyzes the FAD-dependent oxidative deamination of glycine. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate; In the N-terminal section; belongs to the DAO family. ThiO subfamily. | 0.941 |
alr1343 | all3540 | gene:10493358 | gene:10495581 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | 0.999 |
alr1343 | alr3573 | gene:10493358 | gene:10495614 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 0.811 |
alr1343 | alr4129 | gene:10493358 | gene:10496177 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.811 |
alr1343 | asr1344 | gene:10493358 | gene:10493359 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | ORF_ID:asr1344; hypothetical protein. | 0.938 |
alr1343 | moeB | gene:10493358 | gene:10494941 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Molybdopterin biosynthesis protein; ORF_ID:all2906; moeB gene product. | 0.770 |
alr1343 | thiC | gene:10493358 | gene:10492996 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.949 |
alr1343 | thiG | gene:10493358 | gene:10495559 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Thiamin biosynthesis protein; Catalyzes the FAD-dependent oxidative deamination of glycine. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine intermediate (dehydroglycine) required for the biosynthesis of the thiazole ring of thiamine pyrophosphate; In the N-terminal section; belongs to the DAO family. ThiO subfamily. | 0.981 |
alr3525 | thiC | gene:10495565 | gene:10492996 | Phosphoribosylformylglycinamidine cyclo-ligase; ORF_ID:alr3525. | Thiamin biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.813 |
alr3573 | all3540 | gene:10495614 | gene:10495581 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Phosphomethylpyrimidine kinase; ORF_ID:all3540. | 0.423 |
alr3573 | alr1343 | gene:10495614 | gene:10493358 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.811 |
alr3573 | alr4129 | gene:10495614 | gene:10496177 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | 5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine. | 0.998 |
alr3573 | asr1344 | gene:10495614 | gene:10493359 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | ORF_ID:asr1344; hypothetical protein. | 0.749 |
alr3573 | moeB | gene:10495614 | gene:10494941 | 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil. | Molybdopterin biosynthesis protein; ORF_ID:all2906; moeB gene product. | 0.563 |