node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
all2934 | all4774 | gene:10494970 | gene:10496827 | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | Glutaminase; ORF_ID:all4774; putative glutaminase; Belongs to the glutaminase family. | 0.940 |
all2934 | alr0094 | gene:10494970 | gene:10492098 | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.919 |
all2934 | alr2475 | gene:10494970 | gene:10494506 | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.900 |
all2934 | alr4112 | gene:10494970 | gene:10496160 | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
all4774 | all2934 | gene:10496827 | gene:10494970 | Glutaminase; ORF_ID:all4774; putative glutaminase; Belongs to the glutaminase family. | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | 0.940 |
all4774 | alr0094 | gene:10496827 | gene:10492098 | Glutaminase; ORF_ID:all4774; putative glutaminase; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.919 |
all4774 | alr2475 | gene:10496827 | gene:10494506 | Glutaminase; ORF_ID:all4774; putative glutaminase; Belongs to the glutaminase family. | Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.900 |
all4774 | alr4112 | gene:10496827 | gene:10496160 | Glutaminase; ORF_ID:all4774; putative glutaminase; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
all5088 | alr0094 | gene:10497146 | gene:10492098 | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.922 |
alr0092 | alr0093 | gene:10492096 | gene:10492097 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | 0.438 |
alr0092 | alr0094 | gene:10492096 | gene:10492098 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.732 |
alr0092 | alr2270 | gene:10492096 | gene:10494299 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.694 |
alr0092 | alr5045 | gene:10492096 | gene:10497103 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | Penicillin-binding protein; ORF_ID:alr5045. | 0.682 |
alr0092 | alr5065 | gene:10492096 | gene:10497123 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.764 |
alr0093 | alr0092 | gene:10492097 | gene:10492096 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092. | 0.438 |
alr0093 | alr0094 | gene:10492097 | gene:10492098 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.748 |
alr0093 | alr2270 | gene:10492097 | gene:10494299 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.689 |
alr0093 | alr5045 | gene:10492097 | gene:10497103 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | Penicillin-binding protein; ORF_ID:alr5045. | 0.680 |
alr0093 | alr5065 | gene:10492097 | gene:10497123 | N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.762 |
alr0094 | all2934 | gene:10492098 | gene:10494970 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Glutaminase; ORF_ID:all2934; putative glutaminase; Belongs to the glutaminase family. | 0.919 |