STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fraCFilament integrity protein; Involved in filament integrity. Required for the integrity of cell junctions in general but is apparently not directly involved in normal differentiation and nitrogen fixation. (179 aa)    
Predicted Functional Partners:
alr2393
ORF_ID:alr2393; unknown protein.
     
 0.900
alr2394
ORF_ID:alr2394; hypothetical protein.
     
 0.801
alr2338
ORF_ID:alr2338; hypothetical protein.
      
 0.758
patS
Heterocyst-inhibiting signaling peptide; Inhibits heterocyst differentiation. Seems to control heterocyst pattern formation through intercellular signaling mechanisms. In Anabaena filaments every 10th vegetative cell terminally differentiates into a heterocyst specialized for nitrogen fixation. Seems to inhibit the formation of adjacent heterocysts. Inhibits the DNA-binding of HetR.
      
 0.730
mreB
Rod shape-determining protein; ORF_ID:all0087; mreB gene product.
      
 0.725
hetR
Heterocyst differentiation protein; Controls heterocyst differentiation. Has both a protease and a DNA-binding activity. Binds the promoter regions of hetR, hepA and patS.
      
 0.720
mreC
Rod shape-determining protein; ORF_ID:all0086; mreC gene product.
      
 0.660
alr0092
N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0092.
      
 0.659
alr0093
N-acetylmuramoyl-L-alanine amidase; ORF_ID:alr0093.
      
 0.656
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
      
 0.600
Your Current Organism:
Nostoc sp. PCC7120
NCBI taxonomy Id: 103690
Other names: Anabaena sp. (ATCC 27893), Anabaena sp. (PCC 7120), Anabaena sp. DCC D0672, Anabaena sp. PCC 7120, Anabaena sp. SAG 25.82, Anabaena sp. UTEX B 2576, Anabaena variabilis UTCC 387, N. sp. PCC 7120, Nostoc muscorum ISU, Nostoc sp. AKM24, Nostoc sp. ATCC 27347, Nostoc sp. ATCC 72893, Nostoc sp. DSM 107007, Nostoc sp. Ind43, Nostoc sp. PCC 7120, Nostoc sp. SAG 25.82
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