node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
all0262 | alr1004 | gene:10492270 | gene:10493018 | Threonine dehydratase; ORF_ID:all0262. | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. | 0.925 |
all0262 | alr3296 | gene:10492270 | gene:10495334 | Threonine dehydratase; ORF_ID:all0262. | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.920 |
all0262 | alr3338 | gene:10492270 | gene:10495376 | Threonine dehydratase; ORF_ID:all0262. | Phosphoglycerate mutase; ORF_ID:alr3338; Belongs to the phosphoglycerate mutase family. | 0.900 |
all0262 | alr4232 | gene:10492270 | gene:10496281 | Threonine dehydratase; ORF_ID:all0262. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.922 |
all0262 | alr4806 | gene:10492270 | gene:10496859 | Threonine dehydratase; ORF_ID:all0262. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |
all0623 | alr1004 | gene:10492634 | gene:10493018 | Glycolate oxidase subunit (Fe-S) protein; ORF_ID:all0623. | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. | 0.911 |
all4607 | all4608 | gene:10496657 | gene:10496658 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
all4607 | all4609 | gene:10496657 | gene:10496659 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
all4607 | alr1004 | gene:10496657 | gene:10493018 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. | 0.936 |
all4607 | alr2355 | gene:10496657 | gene:10494384 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Alanine dehydrogenase; ORF_ID:alr2355; Belongs to the AlaDH/PNT family. | 0.449 |
all4607 | alr3296 | gene:10496657 | gene:10495334 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.944 |
all4607 | alr4806 | gene:10496657 | gene:10496859 | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
all4608 | all4607 | gene:10496658 | gene:10496657 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
all4608 | all4609 | gene:10496658 | gene:10496659 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
all4608 | alr1004 | gene:10496658 | gene:10493018 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. | 0.922 |
all4608 | alr4806 | gene:10496658 | gene:10496859 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
all4609 | all4607 | gene:10496659 | gene:10496657 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Glycine cleavage system protein P; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
all4609 | all4608 | gene:10496659 | gene:10496658 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
all4609 | alr1004 | gene:10496659 | gene:10493018 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Alanine--glyoxylate aminotransferase; ORF_ID:alr1004. | 0.942 |
all4609 | alr4806 | gene:10496659 | gene:10496859 | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.999 |